微管蛋白折叠辅助因子E样抗体
规格：1mg/1ml
英文名： TBCEL
别名： EL; Leucine-rich repeat-containing protein 35; LRRC35; TBCEL; TBCEL_HUMAN; Tubulin folding cofactor E-like; Tubulin-specific chaperone cofactor E-like protein.
分子量： 48kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human TBCEL
交叉反应：Human, Mouse, Rat,
微管蛋白折叠辅助因子E样抗体细胞定位：细胞浆
产品介绍：background: TBCEL is a 424 amino acid cytoplasmic protein that acts as a regulator of tubulin stability. While abundantly expressed in testis, TBCEL is also present in several tissues at a much lower level. TBCEL contains seven LRR (leucine-rich) repeats, one LRRCT domain and one ubiquitin-like domain. The gene that encodes TBCEL consists of 66,704 bases and maps to human chromosome 11q23.3. Chromosome 11 houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen微管蛋白折叠辅助因子E样抗体 syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that map to chromosome 11. Function: Acts as a regulator of tubulin stability. Subcellular Location: Cytoplasm > cytoskeleton. Tissue Specificity: Abundantly expressed in testis, but is also present in several tissues at a much lower level. Similarity: Contains 7 LRR微管蛋白折叠辅助因子E样抗体 (leucine-rich) repeats. Contains 1 LRRCT domain. Contains 1 ubiquitin-like domain. Database links: Entrez Gene: 219899 Human Omim: 610451 Human SwissProt: Q5QJ74 Human Unigene: 504136 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
微管蛋白折叠辅助因子E样抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid