神经细胞钾氯离子转运蛋白抗体
规格：1mg/1ml
英文名： KCC2
别名： Electroneutral potassium chloride cotransporter 2; Electroneutral potassium-chloride cotransporter 2; Erythroid K Cl cotransporter 2; Erythroid K-Cl cotransporter 2; Furosemide sensitive K Cl cotransp
分子量： 123kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human KCC2
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse,
细胞定位：细胞膜
神经细胞钾氯离子转运蛋白抗体产品介绍：background: K-Cl cotransporters are proteins that lower intracellular chloride concentrations below the electrochemical equilibrium potential. The protein encoded by this gene is an integral membrane K-Cl cotransporter that can function in either a net efflux or influx pathway, depending on the chemical concentration gradients of potassium and chloride. The encoded protein can act as a homomultimer, or as a heteromultimer with other K-Cl cotransporters, to maintain chloride homeostasis神经细胞钾氯离子转运蛋白抗体 in neurons. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Sep 2008] Function: Mediates electroneutral potassium-chloride cotransport in mature neurons. Transport occurs under isotonic conditions, but is activated 20-fold by cell swelling. Important for Cl(-) homeostasis in neurons. Subunit: Homomultimer and heteromultimer with other K-Cl cotransporters.神经细胞钾氯离子转运蛋白抗体 Interacts with AP2A1. Subcellular Location: Membrane; Multi-pass membrane protein. Tissue Specificity: Brain specific. Detected in neuronal cells. Similarity: Belongs to the SLC12A transporter family. Gene ID: 57468 Database links: Entrez Gene: 57468 Human Entrez Gene: 57138 Mouse Entrez Gene: 171373 Rat Omim: 606726 Human SwissProt: Q9H2X9 Human SwissProt: Q91V14 Mouse SwissProt: Q63633 Rat Unigene: 21413 Human Unigene: 252987 Mouse Unigene: 10513 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
神经细胞钾氯离子转运蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 神经生物学 通道蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid