JAZF1抗体
规格：1mg/1ml
英文名： JAZF1
别名： JAZF zinc finger 1; JAZF1; JAZF1_HUMAN; Juxtaposed with another zinc finger protein 1; TAK1 interacting protein 27; TAK1-interacting protein 27; TIP27; Zinc finger protein 802; ZNF802.
分子量： 27kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human JAZF1
交叉反应：Human, Mouse, Rat, Chicken, Pig, Horse, Rabbit, Sheep,
细胞定位：
JAZF1抗体产品介绍：background: This gene encodes a nuclear protein with three C2H2-type zinc fingers, and functions as a transcriptional repressor. Chromosomal aberrations involving this gene are associated with endometrial stromal tumors. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized [provided by RefSeq, Jul 2008] Function: Potential transcription factor. Subunit: Interacts with TAK1. DISEASE: Note=A chromosomal aberration involving JAZF1 may be a cause of endometrial stromal tumors. Translocation t(7;17)(p15;q21) with SUZ12. The translocation generates the JAZF1-SUZ12JAZF1抗体 oncogene consisting of the N-terminus part of JAZF1 and the C-terminus part of SUZ12. It is frequently found in all cases of endometrial stromal tumors, except in endometrial stromal sarcomas, where it is rarer. Translocation t(6;7)(p21;p22) with PHF1. Similarity: Contains 3 C2H2-type zinc fingers. Gene ID: 221895 Database links: Entrez Gene: 221895 Human Entrez Gene: 231986 Mouse Entrez Gene: 685879 Rat OmimJAZF1抗体: 606246 Human SwissProt: Q86VZ6 Human SwissProt: Q80ZQ5 Mouse SwissProt: Q5RDF5 Orangutan Unigene: 368944 Human Unigene: 386865 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. II型糖尿病是危害很大的**，科学家们*近又鉴定出了6个参与II型糖尿病有关的基因。其中JAZF1基因同时在II型糖尿病和前列腺癌中都起作用，但糖尿病和前列腺癌的变异处于基因的不同位置。这些研究将会帮助我们揭示复杂的糖尿病基础，提示**和预防这个**的更好新方法。
JAZF1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid