S100钙结合蛋白A11抗体
规格：1mg/1ml
英文名： S100A11
别名： Calgizzarin; Metastatic lymph node gene 70 protein; MLN 70; MLN70; Protein S100 A11; Protein S100-A11; Protein S100-C; Protein S100A11; Protein S100C; S100 A11; S100 calcium binding protein A11; S100
分子量： 13kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human S100A11
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit,
细胞定位：
S100钙结合蛋白A11抗体产品介绍：background: The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in motility, invasion, and tubulin polymerization.S100钙结合蛋白A11抗体 Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis. [provided by RefSeq] Function: Facilitates the differentiation and the cornification of keratinocytes. Subunit: Homodimer; disulfide-linked. Subcellular Location: Cytoplasm. Nucleus. Post-translational modifications: Phosphorylation at Thr-10 by PRKCA significantly suppresses homodimerizationS100钙结合蛋白A11抗体 and promotes association with NCL/nucleolin which induces nuclear translocation. Similarity: Belongs to the S-100 family. Contains 2 EF-hand domains. Gene ID: 6282 Database links: Entrez Gene: 6282 Human Omim: 603114 Human SwissProt: P31949 Human Unigene: 417004 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
S100钙结合蛋白A11抗体产品应用：IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 **学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid