磷酸化钙调磷酸酶B亚基B1抗体
规格：1mg/1ml
英文名： Phospho-Calcineurin B (Tyr106)
别名： Calcineurin B (phospho Y106); Calcineurin B (phospho Tyr106); p-Calcineurin B (Tyr106); Calcineurin subunit B type 1; CALNB1; CANB1_HUMAN; Cna2; CNB; CNB1; OTTHUMP; OTTHUMP; Ppp3
分子量： 19kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthesised phosphopeptide derived from human
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, Guinea Pig, Fruit Fly, Danio rerio
细胞定位：
磷酸化钙调磷酸酶B亚基B1抗体产品介绍：background: In eukaryotes, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions including division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the protein phosphatases. In general, the protein phosphatase (PP) holoenzyme is a trimeric complex composed of a regulatory subunit, a variable subunit and a catalytic subunit. Four major families of protein 磷酸化钙调磷酸酶B亚基B1抗体phosphatase catalytic subunit have been identified, designated PP1, PP2A, PP2B and PP2C. An additional protein phosphatase catalytic subunit, PPX (also known as PP4), is a putative member of a novel PP family. The PP2B family comprises subfamily members PP2B-A alpha, PP2B-A Beta and PP2B-A Gamma. Two additional regulatory subunits been identified, designated PP2B-B1 and PP2B-B2. Function: Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity. Subunit:磷酸化钙调磷酸酶B亚基B1抗体 Composed of a catalytic subunit (A) and a regulatory subunit (B). Similarity: Belongs to the calcineurin regulatory subunit family. Contains 4 EF-hand domains. Gene ID: 5534 Database links: Entrez Gene: 5534 Human Entrez Gene: 19058 Mouse Entrez Gene: 29748 Rat Omim: 601302 Human SwissProt: P63098 Human SwissProt: Q63810 Mouse SwissProt: P63100 Rat Unigene: 280604 Human Unigene: 41840 Mouse Unigene: 42903 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
磷酸化钙调磷酸酶B亚基B1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid
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