纤维母细胞生长因子受体底物3抗体
规格：1mg/1ml
英文名： FGFR substrate 3
别名： FGFR signalling adaptor SNT2; FGFR substrate 3; Fibroblast growth factor receptor substrate 3; FRS2 beta; FRS2B; FRS3; FRS3 protein; MGC17167; SNT 2; Suc1 associated neurotrophic factor target 2 (FGFR
分子量： 54kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human FGFR sub
交叉反应：Human, Mouse, Rat, Cow, Rabbit, Sheep,
纤维母细胞生长因子受体底物3抗体细胞定位：细胞膜
产品介绍：background: The protein encoded by this gene is a substrate for the fibroblast growth factor receptor. It is found in peripheral plasma membrane and functions in linking FGF receptor stimulation to activators of Ras. [provided by RefSeq, Jul 2008]. Function: Adapter protein that links FGF and NGF receptors to downstream signaling pathways. Involved in the activation of MAP kinases. Down-regulates ERK2 signaling by interfering with the phosphorylation and nuclear translocation of ERK2. Subunit: Binds NTRK1纤维母细胞生长因子受体底物3抗体. Binds FGFR1, NGFR, GRB2, PTPN11 and ERK2. Subcellular Location: Membrane; Lipid-anchor. Tissue Specificity: Phosphorylated by ULK2 in vitro. Phosphorylated on tyrosine residues upon stimulation by BFGF or NGFB. Similarity: Contains 1 IRS-type PTB domain. Gene ID: 10817 Database links: Entrez Gene: 10817 Human Entrez Gene: 107971 Mouse Entrez Gene: 316213 Rat Omim: 607744 Human 纤维母细胞生长因子受体底物3抗体SwissProt: O43559 Human SwissProt: Q91WJ0 Mouse SwissProt: Q52RG8 Rat Unigene: 194208 Human Unigene: 34398 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
纤维母细胞生长因子受体底物3抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：信号转导 生长因子和**
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid