乙型肝炎e抗原抗体
规格：1mg/1ml
英文名： HBeAg
别名： Hepatitis B Virus E Antigen; HBe antigen; HBeAg; HBVgp4; Pre C,C; Precore protein; Precore/core; Precore/core ORF; Precore/core protei; HBEAG_HBVD3; External core antigen; HBeAg; p25.
分子量： 12kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human HBeAg
交叉反应：Hepatitis B virus
乙型肝炎e抗原抗体细胞定位：细胞浆 分泌型蛋白
产品介绍：background: Hepatitis B e-antigen (HBeAg) is a viral protein associated with HBV infections. Unlike the surface antigen, the e-antigen is found in the blood only when there are viruses also present. When the virus goes into “hiding,” the e-antigen will no longer be present in the blood. HBeAg is often used as a marker of ability to spread the virus to other people (infectivity). Measurement of e-antigen may also be used to monitor the effectiveness of HBV treatment; successful treatment will usually eliminate HBeAg from the blood 乙型肝炎e抗原抗体and lead to development of antibodies against e-antigen (anti-HBe). There are some types (strains) of HBV that do not make e-antigen; these are especially common in the Middle East and Asia. In areas where these strains of HBV are common, testing for HBeAg is not very useful. Function: May regulate immune response to the intracellular capsid in acting as a T-cell tolerogen, by having an immunoregulatory effect which prevents destruction of infected cells by cytotoxic T-cells. This immune regulation may predispose to chronicity during perinatal infections and乙型肝炎e抗原抗体 prevent severe liver injury during ***** infections. Subunit: Homodimerizes. Subcellular Location: Secreted. Host nucleus. Post-translational modifications: Phosphorylated. Cleaved by host furin. Similarity: Belongs to the orthohepadnavirus precore antigen family. Gene ID: 944568 Database links: Entrez Gene: 944568 Hepatitis B virus SwissProt: Q89714 Hepatitis B virus Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
乙型肝炎e抗原抗体产品应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 信号转导 生长因子和** 转录调节因子 **细胞
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid