D型**受体抗体
规格:1mg/1ml
英文名: Delta Opioid Receptor
别名: Delta type opioid receptor; Delta type opioid receptor DOR 1; DOR 1; DOR1; mDOR; Nbor; Opioid receptor delta 1; OPRD; OPRD1; OPRD_HUMAN; Delta-type opioid receptor; D-OR-1; DOR-1.
分子量: 41kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human Delta Op
交叉反应:Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, Guinea Pig,
细胞定位:细胞膜
D型**受体抗体产品介绍:background: The opioid receptors are G-protein coupled, seven-transmembrane domain receptors for enkephalins, endorphins, and dynorphins. Three different opioid receptor subtypes (kappa , delta, and mu) were first identified by their different selectivities for various naturally occurring alkaloid opioid ligands, and subsequently confirmed by molecular cloning. The amino acid sequences of the opioid receptor subtypes are ~70% homologous, and are similar to somatostatin receptors (SSTRs) showing ~40 % homology withD型**受体抗体 SSTR1. G-protein binding is thought to occur at the third intracellular loop of the opioid receptors, which is also the location of consensus sequences for phosphorylation of the receptor. Interestingly, the genes encoding the specific receptor subtypes are found on different chromosomes in both the human and mouse genomes. Function: Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Highly stereoselective. receptor for enkephalins. Subunit: Interacts with GPRASP1. Subcellular Location: Cell membrane; Multi-pass membrane protein. Tissue Specificity: Abundant in lymphoid tissues. Post-translational modifications: Glycosylation is tissue specific. Sialylation of N-glycansD型**受体抗体 at Asn-93 in brain and at Asn-42, Asn-93 and Asn-117 in thymus. Similarity: Belongs to the G-protein coupled receptor 1 family. Gene ID: 4985 Database links: Entrez Gene: 4985 Human Entrez Gene: 18386 Mouse Entrez Gene: 24613 Rat Omim: 165195 Human SwissProt: P41143 Human SwissProt: P32300 Mouse SwissProt: P33533 Rat Unigene: 372 Human Unigene: 10310 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
D型**受体抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 **学 神经生物学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid