瞬时受体电位通道1抗体
规格:1mg/1ml
英文名: TRPC1
别名: TRPC1_HUMAN; Short transient receptor potential channel 1; TrpC1; Transient receptor protein 1; TRP-1; TRP 1; TRP 1 protein; TRP1; TRP1 protein; . HTRP 1; HTRP1; MGC133334; MGC133335; Mtrp1; Transient
分子量: 87kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human TRPC1
交叉反应:Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit,
细胞定位:
瞬时受体电位通道1抗体产品介绍:background: The protein encoded by this gene is a membrane protein that can form a non-selective channel permeable to calcium and other cations. The encoded protein appears to be induced to form channels by a receptor tyrosine kinase-activated phosphatidylinositol second messenger system and also by depletion of intracellular calcium stores. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]. Function: Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine 瞬时受体电位通道1抗体kinases or G-protein coupled receptors. Seems to be also activated by intracellular calcium store depletion. Subunit: Interacts with TRPC4AP. Homotetramer and heterotetramer with TRPC4 and/or TRPC5. Interacts with TRPC3, TRPC4 and TRPC5. Interacts with ITPR3. Interacts with MX1 and RNF24. Interacts with FKBP4. Subcellular Location: Membrane; Multi-pass membrane protein. Tissue Specificity: Seems to be ubiquitous. Similarity: Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily. TRPC1 sub-subfamily. Contains 4 ANK repeats. Gene ID: 7220 瞬时受体电位通道1抗体Database links: Entrez Gene: 7220 Human Entrez Gene: 22063 Mouse Entrez Gene: 89821 Rat Omim: 602343 Human SwissProt: P48995 Human SwissProt: Q61056 Mouse SwissProt: Q9QX01 Rat Unigene: 250687 Human Unigene: 149633 Mouse Unigene: 88592 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
瞬时受体电位通道1抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid