血小板生成素/巨核细胞集落刺激因子抗体
规格：1mg/1ml
英文名： Thrombopoietin
别名： c mpl ligand; C-mpl ligand; Megakaryocyte Colony Stimulating Factor; Megakaryocyte colony-stimulating factor; Megakaryocyte growth and development factor; Megakaryocyte stimulating factor; MGDF; MKCSF
分子量： 37kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Thrombop
交叉反应：Human, Mouse, Rat, Cow, Sheep,
细胞定位：分泌型蛋白
血小板生成素/巨核细胞集落刺激因子抗体产品介绍：background: Megakaryocytopoiesis is the cellular development process that leads to platelet production. The protein encoded by this gene is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. This protein is the ligand for MLP/C_MPL, the product of myeloproliferative leukemia virus oncogene. Mutations in this gene are the cause of thrombocythemia 1. Alternate splicing results in multiple transcript variants of this gene.[provided by RefSeq血小板生成素/巨核细胞集落刺激因子抗体, Jun 2012]. Function: Lineage-specific cytokine affecting the proliferation and maturation of megakaryocytes from their committed progenitor cells. It acts at a late stage of megakaryocyte development. It may be the major physiological regulator of circulating platelets. Subcellular Location: Secreted. DISEASE: Thrombocythemia 1 (THCYT1) [MIM:187950]: A myeloproliferative disorder characterized by excessive platelet production, resulting in increased numbers of circulating platelets. It can be associated with spontaneous hemorrhages and thrombotic episodes. Note=The disease is caused by mutations affecting the gene represented in this entry. Similarity: Belongs to the EPO/TPO family. Database 血小板生成素/巨核细胞集落刺激因子抗体links: NCBI Reference Sequence: NP_000451.1 UniProtKB/Swiss-Prot: P40225.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
血小板生成素/巨核细胞集落刺激因子抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 心血管 细胞生物 干细胞 细胞周期蛋白 细胞分化
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid