β1,3半乳糖转移酶3抗体
规格:1mg/1ml
英文名: B3GALNT1
别名: 3-galactosyltransferase 3; 3-GalNAc-T1; 3-GalTase 3; 3-N-acetylgalactosaminyltransferase 1; 3-N-acetylgalactosaminyltransferase; b3Gal T3; b3Gal-T3; B3galnt1; B3GALT3; B3GL1_HUMAN; Beta 1,3 galactosyl
分子量: 39kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human B3GALNT1
交叉反应:Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit,
细胞定位:细胞浆 细胞膜
β1,3半乳糖转移酶3抗体产品介绍:background: This gene is a member of the beta-1,3-galactosyltransferase (beta3GalT) gene family. This family encodes type II membrane-bound glycoproteins with diverse enzymatic functions using different donor substrates (UDP-galactose and UDP-N-acetylglucosamine) and different acceptor sugars (N-acetylglucosamine, galactose, N-acetylgalactosamine). The beta3GalT genes are distantly related to the Drosophila Brainiac gene and have the protein coding sequence contained in a single exon. The beta3GalT proteins also contain conserved sequences not found in the beta4GalT or alpha3GalT proteins. The carbohydrate chains synthesized by these enzymes are designated as type 1, whereas beta4GalT enzymes synthesize type 2 carbohydrate chains. The ratio of type 1:type 2 chains changes during embryogenesis.β1,3半乳糖转移酶3抗体 By sequence similarity, the beta3GalT genes fall into at least two groups: beta3GalT4 and 4 other beta3GalT genes (beta3GalT1-3, beta3GalT5). The encoded protein of this gene does not use N-acetylglucosamine as an acceptor sugar at all. Multiple transcript variants that are alternatively spliced in the 5' UTR have been described; they all encode the same protein. Function: Transfers N-acetylgalactosamine onto globotriaosylceramide. Subcellular Location: Golgi apparatus membrane; Single-pass type II membrane protein. Tissue Specificity: Higher expressionβ1,3半乳糖转移酶3抗体 in heart and brain, and to a lesser extent in lung, placenta, kidney and testis. Lower expression in liver, spleen and stomach. Similarity: Belongs to the glycosyltransferase 31 family. Gene ID: 8706 Database links: Entrez Gene: 8706 Human Entrez Gene: 26879 Mouse Entrez Gene: 310508 Rat Omim: 603094 Human SwissProt: O75752 Human SwissProt: Q920V1 Mouse SwissProt: Q6AY39 Rat Unigene: 418062 Human Unigene: 153710 Mouse Unigene: 3666 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
β1,3半乳糖转移酶3抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:心血管 细胞生物
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid