微粒体谷胱甘肽S转移酶1抗体
规格：1mg/1ml
英文名： MGST1
别名： MGST1; Glutathione S transferase 12; Microsomal glutathione transferase 1; GST12; MGST 1; MGST; MGST1; MGST1_HUMAN; Microsomal glutathione S-transferase 1; Microsomal GST 1; Microsomal GST-1; Microsom
分子量： 17kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human MGST1
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
微粒体谷胱甘肽S转移酶1抗体细胞定位：细胞浆 细胞膜
产品介绍：background: The MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) family consists of six human proteins, two of which are involved in the production of leukotrienes and prostaglandin E, important mediators of inflammation. Other family members, demonstrating glutathione S-transferase and peroxidase activities, are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. This gene encodes a protein that catalyzes the conjugation of glutathione to electrophiles and the reduction of lipid hydroperoxides. This protein is localized to the endoplasmic reticulum and outer mitochondrial membrane where it is thought to微粒体谷胱甘肽S转移酶1抗体 protect these membranes from oxidative stress. Several transcript variants, some non-protein coding and some protein coding, have been found for this gene. [provided by RefSeq, May 2012] Function: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Has a wide substrate specificity. Subcellular Location: Microsome. Mitochondrion outer membrane. Endoplasmic reticulum membrane. Tissue Specificity: Highly expressed in liver. Post-translational modifications: Peroxynitrite induces nitration at Tyr-93 which activates the enzyme. Similarity: Belongs to the MAPEG family. Gene ID: 4257 Database links: Entrez Gene: 4257 Human Entrez Gene: 56615 Mouse Entrez 微粒体谷胱甘肽S转移酶1抗体Gene: 171341 Rat Omim: 138330 Human SwissProt: P10620 Human SwissProt: Q91VS7 Mouse SwissProt: P08011 Rat Unigene: 389700 Human Unigene: 14796 Mouse Unigene: 2580 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
微粒体谷胱甘肽S转移酶1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：神经生物学 信号转导 Alzheimer's
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid