臂板蛋白3A抗体
规格：1mg/1ml
英文名： Sema3A
别名： Semaphorin 3A; Semaphorin-3A; Semaphorin-3A precursor; Semaphorin3A; SemD; Sema 3A; SEM3A_MOUSE; Coll 1; Coll1; Hsema I; Hsema III; sema domain immunoglobulin domain (Ig) short basic domain secreted (
分子量： 86kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Sema3A
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Horse, Rabbit, Sheep,
细胞定位：分泌型蛋白
臂板蛋白3A抗体产品介绍：background: This gene is a member of the semaphorin family and encodes a protein with an Ig-like C2-type (immunoglobulin-like) domain, a PSI domain and a Sema domain. This secreted protein can function as either a chemorepulsive agent, inhibiting axonal outgrowth, or as a chemoattractive agent, stimulating the growth of apical dendrites. In both cases, the protein is vital for normal neuronal pattern development. Increased expression of this protein is associated with schizophrenia and is seen in a variety of臂板蛋白3A抗体 human tumor cell lines. Also, aberrant release of this protein is associated with the progression of Alzheimer's disease. Function: Plays a role in growth cones guidance. May function to pattern sensory projections by selectively repelling axons that normally terminate dorsally. Involved in the development of the olfactory system and in neuronal control of puberty. Subunit: Interacts with PXND1. Subcellular Location: Secreted. Tissue Specificity: Expressed at relatively high levels in brain and muscle, moderate levels in lung, bursa, and heart and virtually absent in liver. Collapsin-1, -2, -3, and -5 bind to overlapping but distinct axon tracts. Similarity: Belongs to the semaphorin family. Contains 1 Ig-like C2-type (immunoglobulin-like) domain. Contains 1 PSI domain. Contains 1 Sema domain. Gene ID: 20346 Database links: Entrez Gene: 10371 Human Entrez Gene:臂板蛋白3A抗体 20346 Mouse Entrez Gene: 29751 Rat Omim: 603961 Human SwissProt: Q14563 Human SwissProt: O08665 Mouse SwissProt: Q5BL08 Mouse SwissProt: Q63548 Rat Unigene: 252451 Human Unigene: 44410 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
臂板蛋白3A抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：神经生物学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid