Minibrain 抗体
规格：1mg/1ml
英文名： Minibrain
别名： MNB_DROME; Serine/threonine-protein kinase minibrain; mnb; Dmel_CG42273; Dmel_CG7826; Dmel_CG7835; CG42273; CG7826; CG7835; Dm1; Dmel\CG42273; Dyrk1; DYRK1; ME-IV; min; Mnb; MNB.
分子量： 96kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Minibrai
交叉反应：Fruit Fly,
细胞定位：细胞核
Minibrain 抗体产品介绍：background: This gene encodes a member of the Dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) family. This member contains a nuclear targeting signal sequence, a protein kinase domain, a leucine zipper motif, and a highly conservative 13-consecutive-histidine repeat. It catalyzes its autophosphorylation on serine/threonine and tyrosine residues. It may play a significant role in a signaling pathway regulating cell proliferation and may be involved in brain development. This gene is a homolog of Drosophila mnb (minibrain) gene and rat Dyrk gene. It is localized in the Down syndrome critical region of chromosome 21, and is considered to be a strong candidate gene for Minibrain 抗体earning defects associated with Down syndrome. Alternative splicing of this gene generates several transcript variants differing from each other either in the 5' UTR or in the 3' coding region. These variants encode at least five different isoforms. [provided by RefSeq, Jul 2008] Function: Role in the specific control of proper proliferation of optic lobe neuronal progeny. Subcellular Location: Nucleus (Potential). Tissue Specificity: In ventralMinibrain 抗体 nerve cord and supraesophageal ganglion of embryos. Is most prominent in the mushroom body neuropil and the outer proliferation center of the optic lobes in third instar larvae. Similarity: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily. Contains 1 protein kinase domain. Gene ID: 32771 Database links: Entrez Gene: 32771 DROME Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Minibrain 抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：昆虫
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid