单纯疱疹病毒1型DNA聚合酶催化亚单位抗体
规格:1mg/1ml
英文名: HHV11 DNA polymerase catalytic subunit
别名: DPOL_HHV11; DNA polymerase catalytic subunit; UL30; HHV1gp046.
分子量: 136kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human HHV11 DN
交叉反应:Herpes simplex virus (type 1 / strain 17)
细胞定位:细胞核
单纯疱疹病毒1型DNA聚合酶催化亚单位抗体产品介绍:Function: Replicates viral genomic DNA. The replication complex is composed of six viral proteins: the DNA polymerase, processivity factor, primase, primase-associated factor, helicase, and ssDNA-binding protein. Additionally, the polymerase contains an intrinsic ribonuclease H (RNase H) activity that specifically degrades RNA/DNA heteroduplexes or duplex DNA substrates in the 5' to 3' direction. Therefore, it can catalyze the excision of the RNA primers that initiate the synthesis of Okazaki 单纯疱疹病毒1型DNA聚合酶催化亚单位抗体fragments at a replication fork during viral DNA replication. Subunit: Forms a complex with the ssDNA-binding protein UL29, the DNA polymerase processivity factor, and the alkaline exonuclease. Interacts with the putative helicase-primase complex subunit UL8; this interaction may coordinate leading and lagging strand DNA synthesis at the replication fork (By similarity). Subcellular 单纯疱疹病毒1型DNA聚合酶催化亚单位抗体Location: Host nucleus (Potential). Note=The protein is present at discrete sites in nuclei, called replication compartments where viral DNA replication occurs (By similarity). Similarity: Belongs to the DNA polymerase type-B family. Database links: UniProtKB/Swiss-Prot: P04293 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
单纯疱疹病毒1型DNA聚合酶催化亚单位抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:微生物学 **及病毒
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid