CD3抗体
规格：1mg/1ml
英文名： CD3
别名： CD 3E; CD3 epsilon; CD3 TCR complex; CD3E; CD3e antigen epsilon polypeptide (TiT3 complex); CD3E antigen epsilon polypeptide; CD3e molecule epsilon; CD3E_pig; T cell antigen receptor complex epsilon s
分子量： 20kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from pig CD3
交叉反应：Pig,
细胞定位：细胞膜
CD3抗体产品介绍：background: The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. CD3抗体[provided by RefSeq, Jul 2008]. Function: The CD3 complex mediates signal transduction. Subunit: The TCR/CD3 complex of T-lymphocytes consists of either a TCR alpha/beta or TCR gamma/delta heterodimer coexpressed at the cell surface with the invariant subunits of CD3 labeled gamma, delta, epsilon, zeta, and eta. Subcellular Location: Membrane; Single-pass type I membrane protein. Similarity: Contains 1 Ig-like (immunoglobulin-like) domain. Contains 1 ITAM domain. Gene ID: 397455 Database links: Entrez Gene: 915 Human Entrez Gene: 916 Human Entrez Gene: 917 Human Entrez Gene: 919 Human Entrez Gene: 12500 Mouse Entrez Gene: 12501 Mouse Entrez Gene: 12502 Mouse Entrez Gene: 12503 Mouse Entrez Gene:CD3抗体 25300 Rat Entrez Gene: 25710 Rat Entrez Gene: 300678 Rat Entrez Gene: 315609 Rat Omim: 186740 Human Omim: 186780 Human Omim: 186790 Human Omim: 186830 Human SwissProt: P04234 Human SwissProt: P07766 Human SwissProt: P09693 Human SwissProt: P20963 Human SwissProt: P04235 Mouse SwissProt: P11942 Mouse SwissProt: P22646 Mouse SwissProt: P24161 Mouse SwissProt: P29020 Mouse SwissProt: P19377 Rat SwissProt: Q64159 Rat Unigene: 156445 Human Unigene: 2259 Human Unigene: 3003 Human Unigene: 504048 Human Unigene: 210361 Mouse Unigene: 335106 Mouse Unigene: 4527 Mouse Unigene: 10329 Rat Unigene: 96221 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
CD3抗体产品应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学 糖蛋白 t-**细胞
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid