长链脂肪酸转运蛋白1抗体
规格:1mg/1ml
英文名: SLC27A1
别名: FATP1; ACSVL5; FATP 1; FATP; Fatty acid transport protein 1; Long chain fatty acid transport protein 1; Solute carrier family 27 (fatty acid transporter) member 1; Solute carrier family 27 member 1; S
分子量: 71kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human SLC27A1
交叉反应:Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep,
细胞定位:细胞浆 细胞膜
长链脂肪酸转运蛋白1抗体产品介绍:background: SLC27A1 (Solute carrier family 27 member 1) is involved in translocation of long-chain fatty acids (LFCA) across the plasma membrane. SLC27A1 may act directly as a bona fide transporter, or alternatively, in a cytoplasmic or membrane-associated multimeric protein complex to trap and draw fatty acids towards accumulation. It also plays a pivotal role in regulating available LFCA substrates from exogenous sources in tissues undergoing high levels of beta-oxidation or triglyceride synthesis and may be involved in regulation of cholesterol metabolism. Function: Thin filament-associated protein that is implicated in the regulation and 长链脂肪酸转运蛋白1抗体modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. Subunit: Self-associates. May function as a homodimer. Subcellular Location: Cell membrane; Single-pass membrane protein. Endomembrane system; Single-pass membrane protein. Cytoplasm. Note=Plasma membrane and intracellular membranes, at least in adipocytes. Predominantly cytoplasmic in myocytes. Tissue Specificity: Highest levels of expression 长链脂肪酸转运蛋白1抗体are detected in muscle and adipose tissue small, intermediate levels in small intestine, and barely detectable in liver. Similarity: Belongs to the calponin family. Contains 3 calponin-like repeats. Contains 1 CH (calponin-homology) domain. Gene ID: 376497 Database links: Entrez Gene: 376497 Human Entrez Gene: 26457 Mouse Omim: 600691 Human SwissProt: Q6PCB7 Human SwissProt: Q60714 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
长链脂肪酸转运蛋白1抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid