骨骼肌慢肌肌钙蛋白I抗体
规格：1mg/1ml
英文名： Tnni1
别名： Troponin I, slow skeletal muscle; SSTNI; TNN1; TNNI1_MOUSE; Troponin I slow skeletal muscle; Troponin I, slow twitch isoform.
分子量： 21kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Tnni1
交叉反应：Mouse, Rat,
细胞定位：
骨骼肌慢肌肌钙蛋白I抗体产品介绍：background: Troponin proteins associate with tropomyosin and regulate the calcium sensitivity of the myofibril contractile apparatus of striated muscles. Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. The TnI-fast and TnI-slow genes are expressed in fast-twitch and slow-twitch skeletal muscle fibers, respectively, while the TnI-cardiac gene is expressed exclusively in cardiac muscle tissue. This gene encodes the Troponin-I-skeletal-slow-twitch protein. This gene is expressed in cardiac骨骼肌慢肌肌钙蛋白I抗体 and skeletal muscle during early development but is restricted to slow-twitch skeletal muscle fibers in *****s. The encoded protein prevents muscle contraction by inhibiting calcium-mediated conformational changes in actin-myosin complexes. [provided by RefSeq, Jul 2008]. Function: Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. Subunit: Binds to actin and tropomyosin. Similarity: Belongs to the troponin I family. Gene ID: 7135 Database links: Entrez Gene: 骨骼肌慢肌肌钙蛋白I抗体7135 Human Entrez Gene: 7136 Human Entrez Gene: 21952 Mouse Entrez Gene: 21953 Mouse Omim: 191042 Human Omim: 191043 Human SwissProt: P19237 Human SwissProt: P48788 Human SwissProt: P13412 Mouse SwissProt: Q9WUZ5 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
骨骼肌慢肌肌钙蛋白I抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid