鼻咽癌细胞相关基因6抗体
规格：1mg/1ml
英文名： C9orf127
别名： NGX6; 4930500O05Rik; C9orf127; MGC120460; NAG-5; NGX6; RGD1310012; RP11-112J3.10; TMEM8B; nasopharyngeal carcinoma; NPC associated gene 6; TMM8B_HUMAN; chromosome 9 open reading frame 127; NAG 5; Naso
分子量： 52kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human NGX6 N-t
交叉反应：Human, Mouse, Rat, Cow,
鼻咽癌细胞相关基因6抗体细胞定位：细胞核 细胞浆 细胞膜
产品介绍：background: NGX6 (nasopharyngeal carcinoma/NPC associated gene 6) may function as a regulator of the EGFR pathway. Probable tumor suppressor which may function in cell growth, proliferation and adhesion. [SUBUNIT] Isoform 2 (via its cytoplasmic part) interacts with EZR. [SUBCELLULAR LOCATION] Isoform 2: Cell membrane; Multi-pass membrane protein (Probable). Cytoplasm (Probable). Nucleus (Probable). Mitochondrion. Endoplasmic reticulum. Belongs to the NGX6 family. The down-regulation of C9orf127 may be closely associated with tumorigenesis and metastasis of colorectal carcinoma. However, it may not contribute to the development and progression鼻咽癌细胞相关基因6抗体 of gastric carcinoma. Function: May function as a regulator of the EGFR pathway. Probable tumor suppressor which may function in cell growth, proliferation and adhesion. Subunit: Isoform 2 (via its cytoplasmic part) interacts with EZR. Subcellular Location: Cell membrane. Cytoplasm. Nucleus. Mitochondrion. Endoplasmic reticulum. Also detected in mitochondrion and endoplasmic reticulum. Post-translational modifications: Isoform 2 is N-glycosylated. Similarity: Belongs to the TMEM8 family. Contains 1 EGF-like domain. Gene ID: 51754 Database links: Entrez 鼻咽癌细胞相关基因6抗体Gene: 51754 Human Entrez Gene: 100125302 Cow Entrez Gene: 242409 Mouse Entrez Gene: 313490 Rat SwissProt: A6QLK4 Cow SwissProt: A6NDV4 Human SwissProt: B1AWJ5 Mouse Unigene: 493808 Human Unigene: 171489 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. NGX6是鼻咽癌发生和发展重要的相关蛋白,NGX-6作用于鼻咽癌细胞，抗体可用于鼻咽癌诊断。有学者认为：NGX6也表达在部分消化系统的肿瘤中。
鼻咽癌细胞相关基因6抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 转录调节因子
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid