肿瘤坏死因子配体超家族成员4抗体
规格:1mg/1ml
英文名: TNFSF4
别名: CD 134L; CD 252; CD134; CD134 ligand; CD134L; CD252; CD252 antigen; glycoprotein 34 kd; Glycoprotein Gp34; GP34; OX-40L; OX40 antigen ligand; OX40 ligand; OX40L; TAX transcriptionally-activated glycop
分子量: 22kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from rat TNFSF4
交叉反应:Mouse, Rat,
细胞定位:细胞膜
肿瘤坏死因子配体超家族成员4抗体产品介绍:background: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent 肿瘤坏死因子配体超家族成员4抗体B cell proliferation and differentiation. [provided by RefSeq] Function: Cytokine that binds to TNFRSF4. Co-stimulates T-cell proliferation and cytokine production. Subunit: Homotrimer (Probable). Subcellular Location: Membrane; Single-pass type肿瘤坏死因子配体超家族成员4抗体 II membrane protein. Tissue Specificity: Detected in T-cell lines, but not in a macrophage cell line. Similarity: Belongs to the tumor necrosis factor family. Gene ID: 89814 Database links: Entrez Gene: 7292 Human Entrez Gene: 22164 Mouse Entrez Gene: 89814 Rat Omim: 603594 Human SwissProt: P23510 Human SwissProt: P43488 Mouse SwissProt: Q9Z2P3 Rat Unigene: 181097 Human Unigene: 4994 Mouse Unigene: 30043 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
肿瘤坏死因子配体超家族成员4抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 **学 细胞表面分子 **细胞 t-**细胞 细胞因子
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid