驱动蛋白家族成员15抗体
规格:1mg/1ml
英文名: KIF15
别名: Kinesin like protein 7; KLP2; FLJ25667; HKLP2; Kinesin family member 15; Kinesin like protein 2; Kinesin like protein 7; Kinesin like protein KIF15; KLP2; KNSL7; Linesin like 7; NY BR 62; NYBR62; Sero
分子量: 160kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human KIF15
交叉反应:Human, Mouse, Rat, Dog, Horse,
细胞定位:细胞浆 细胞膜 分泌型蛋白
驱动蛋白家族成员15抗体产品介绍:background: KIF15 belongs to the kinesin-like protein family and contains 1 kinesin-motor domain. KIF15 is the plus-end directed kinesin-like motor enzyme involved in mitotic spindle assembly. Function: Plus-end directed kinesin-like motor enzyme involved inmitotic spindle assembly. Subunit: Interacts with MKI67 and TPX2. Subcellular Location: Cytoplasm. Cytoplasm, cytoskeleton, spindle.Note=Detected during the interphase in the cytoplasm as finelypunctuate pattern and irregularly shaped dots. Detected duringmitosis驱动蛋白家族成员15抗体 on the mitotic spindle. Colocalizes with TPX2 in mitosis.Localizes at the central spindle at anaphase.Localizes at the sites of invaginating cell membranes, a positionthat corresponds to the location of the contractile actomyosin ringof dividing cells. Colocalizes with actin ininterphase. Colocalizes in dendrites and in growthcone of axons with microtubules. Tissue Specificity: Highly expressed in liver and weakly in testis. Expression was higher in patients with severe fibrosis or inflammation and chronic hepatitis. Similarity: Belongs to the kinesin-like protein family. 驱动蛋白家族成员15抗体KLP2subfamily. Contains 1 kinesin-motor domain. Gene ID: 56992 Database links: Entrez Gene: 56992 Human Entrez Gene: 209737 Mouse Entrez Gene: 353302 Rat SwissProt: Q9NS87 Human SwissProt: Q6P9L6 Mouse SwissProt: Q7TSP2 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
驱动蛋白家族成员15抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 细胞骨架 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid