FC段IgE受体α多肽/Fc ε RIα抗体
规格:1mg/1ml
英文名: FCER1A
别名: FCER 1A; IgE Fc receptor alpha subunit; Fc epsilon RI alpha; Fc epsilon RI alpha chain; Fc fragment of IgE high affinity I receptor for alpha polypeptide; Fc IgE receptor alpha polypeptide; Fc of IgE
分子量: 27kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human FCER1A
交叉反应:Human,
细胞定位:细胞膜
FC段IgE受体α多肽/Fc ε RIα抗体产品介绍:background: The immunoglobulin epsilon receptor (IgE receptor) is the initiator of the allergic response. When two or more high-affinity IgE receptors are brought together by allergen-bound IgE molecules, mediators such as histamine that are responsible for allergy symptoms are released. This receptor is comprised of an alpha subunit, a beta subunit, and two gamma subunits. The protein encoded by this gene represents the alpha subunit. [provided by RefSeq, Aug 2011] Function: Binds to the Fc region of FC段IgE受体α多肽/Fc ε RIα抗体immunoglobulins epsilon. High affinity receptor. Responsible for initiating the allergic response. Binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators (such as histamine) responsible for the manifestations of allergy. The same receptor also induces the secretion of important lymphokines. Subcellular Location: Cell membrane; Single-pass type FC段IgE受体α多肽/Fc ε RIα抗体I membrane protein. Similarity: Contains 2 Ig-like (immunoglobulin-like) domains. Gene ID: 2205 Database links: Entrez Gene: 2205 Human Omim: 147140 Human SwissProt: P12319 Human Unigene: 897 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
FC段IgE受体α多肽/Fc ε RIα抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 **学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid