硫酸乙酰肝素6脑苷脂转硫酸酶1抗体
规格:1mg/1ml
英文名: HS6ST1
别名: 6OST 1; 6OST1; DKFZp547H098; FLJ25392; H6 ST1; H6ST 1; H6ST1_HUMAN; Heparan sulfate 6 O sulfotransferase 1; Heparan sulfate 6 sulfotransferase; Heparan sulphate 6 O sulphotransferase 1; Heparan-sulfat
分子量: 48kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human HS6ST1
交叉反应:Human, Mouse, Rat, Dog, Horse, Rabbit,
细胞定位:细胞膜
硫酸乙酰肝素6脑苷脂转硫酸酶1抗体产品介绍:background: Heparan sulfate structures, which are responsible for executing multiple biologic activities, are generated and regulated by heparan sulfate (HS) biosynthetic enzymes. HS6ST1 (heparan sulfate 6-O-sulfotransferase 1), also known as HS6ST, is a 411 amino acid single-pass type II membrane protein that exists as multiple alternatively spliced isoforms and belongs to the sulfotransferase 6 family. Expressed in fetal brain, HS6ST1 functions as a 6-O-sulfation enzyme that specifically catalyzes the transfer硫酸乙酰肝素6脑苷脂转硫酸酶1抗体 of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to the N-sulfoglucosamine residue (GlcNS) HS. HS6ST1 is subject to post-translational N-glycosylation and is encoded by a functional gene on human chromosome 2 and a pseudogene on human chromosome 1 (known as LOC728969). Function: 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine硫酸乙酰肝素6脑苷脂转硫酸酶1抗体 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate. Subcellular Location: Membrane; Single-pass type II membrane protein Tissue Specificity: Expressed in fetal brain. Post-translational modifications: N-glycosylated. Similarity: Belongs to the sulfotransferase 6 family. Gene ID: 9394 Database links: Entrez Gene: 9394 Human Entrez Gene: 50785 Mouse Omim: 604846 Human SwissProt: O60243 Human SwissProt: Q9QYK5 Mouse Unigene: 512841 Human Unigene: 213566 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
硫酸乙酰肝素6脑苷脂转硫酸酶1抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 神经生物学 信号转导 生长因子和**
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid