谷氨酸受体2D抗体
规格：1mg/1ml
英文名： NR2D
别名： Glutamate [NMDA] receptor subunit epsilon 4; Grin2d; N-methyl D-aspartate receptor subtype 2D; NMDAR2D; NMDE4; NR2D; NMDE4_HUMAN; Glutamate [NMDA] receptor subunit epsilon-4; EB11.
分子量： 143kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human NR2D
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow,
细胞定位：细胞膜
谷氨酸受体2D抗体产品介绍：background: NR2D is a NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. NR2D is expressed in the brain; it is detected in embryonic stages, peaks at postnatal day 7, and decreases thereafter to ***** levels. [FUNCTION] NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. [SUBUNIT] Forms heteromeric channel of a zeta subunit (GRIN1), a epsilon subunit (GRIN2A, GRIN2B, GRIN2C or GRIN2D) and a third subunit (GRIN3A or GRIN3B). Interacts with PDZ domains of INADL and DLG4.谷氨酸受体2D抗体 [SUBCELLULAR LOCATION] Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. [TISSUE SPECIFICITY] Expressed in brain, mainly in the subcortical region. [SIMILARITY] Belongs to the glutamate-gated ion channel. Subunit: Interacts with PDZ domains of INADL and DLG4 (By similarity). Forms heteromeric channel of a zeta subunit (GRIN1), a epsilon subunit (GRIN2A, GRIN2B, GRIN2C or GRIN2D) and a third subunit (GRIN3A or GRIN3B). Subcellular Location: Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Similarity: Belongs to the glutamate-gated ion channel 谷氨酸受体2D抗体(TC 1.A.10.1) family. NR2D/GRIN2D subfamily. Gene ID: 2906 Database links: Entrez Gene: 2906 Human Entrez Gene: 14814 Mouse Entrez Gene: 24412 Rat Omim: 602717 Human SwissProt: O15399 Human SwissProt: Q03391 Mouse SwissProt: Q62645 Rat Unigene: 445015 Human Unigene: 91209 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 谷氨酸受体2D（NR2D 又称作Glutamate Receptor NMDAR2D;Glutamate receptor；N-Methyl-d-Asprtate receptor-2D）是脊椎动物**神经系统兴奋型神经传递的主要介质。在突触可塑性极大脑学习及记忆功能方面起关键作用。
谷氨酸受体2D抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：神经生物学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid