SLC19A2抗体
规格：1mg/1ml
英文名： SLC19A2
别名： Thiamine transporter 1; S19A2_HUMAN; SLC19A2; Solute carrier family 19 member 2; TC1; Thiamine carrier 1; THT1; ThTr 1; ThTr-1; ThTr1; TRMA.
分子量： 55kDa
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human SLC19A2
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit,
细胞定位：细胞膜
SLC19A2抗体产品介绍：background: This gene encodes the thiamin transporter protein. Mutations in this gene cause thiamin-responsive megaloblastic anemia syndrome (TRMA), which is an autosomal recessive disorder characterized by diabetes mellitus, megaloblastic anemia and sensorineural deafness. [provided by RefSeq, Jul 2008] Function: High-affinity transporter for the intake of thiamine.SLC19A2抗体 Subcellular Location: Membrane. Tissue Specificity: Ubiquitous; most abundant in skeletal and cardiac muscle. Medium expression in placenta, heart, liver and kidney, low in lung. DISEASE: Defects in SLC19A2 are the cause of thiamine-responsive megaloblastic anemia syndrome (TRMA) [MIM:249270]; also known as Rogers syndrome. TRMA is an autosomal recessive disease with features that include megaloblastic anemia, mild thrombocytopenia and leucopenia, sensorineural deafness and diabetes mellitus. Similarity: Belongs to the reduced folateSLC19A2抗体 carrier (RFC) transporter (TC 2.A.48) family. Gene ID: 10560 Database links: Entrez Gene: 10560 Human Entrez Gene: 116914 Mouse Entrez Gene: 289175 Rat Omim: 603941 Human SwissProt: O60779 Human SwissProt: Q9EQN9 Mouse SwissProt: Q499Q0 Rat Unigene: 30246 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
SLC19A2抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 信号转导 新陈代谢
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid