X连锁Charcot-Marie-Tooth神经病变相关蛋白抗体
规格:1mg/1ml
英文名: GARS
别名: AP 4 A synthetase; Charcot Marie Tooth neuropathy 2D; Charcot Marie Tooth neuropathy neuronal type D; CMT2D; Diadenosine tetraphosphate synthetase; DSMAV; EC 6.1.1.14; Glycine tRNA ligase; Glycyl tRNA
分子量: 83kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human GARS
交叉反应:Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Sheep,
细胞定位:细胞核 细胞浆
X连锁Charcot-Marie-Tooth神经病变相关蛋白抗体产品介绍:background: This gene encodes glycyl-tRNA synthetase, one of the aminoacyl-tRNA synthetases that charge tRNAs with their cognate amino acids. The encoded enzyme is an (alpha)2 dimer which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseasesX连锁Charcot-Marie-Tooth神经病变相关蛋白抗体, polymyositis or dermatomyositis. [provided by RefSeq, Jul 2008] Function: GARS synthetase catalyzes the ligation of glycine with glycyl-tRNA using ATP and its mutation induces Charcot-Marie-Tooth (CMT) disease. Subcellular Location:X连锁Charcot-Marie-Tooth神经病变相关蛋白抗体 Cytoplasmic. Gene ID: 2617 Database links: Entrez Gene: 2617 Human Entrez Gene: 353172 Mouse Entrez Gene: 297113 Rat Omim: 600287 Human SwissProt: P41250 Human SwissProt: Q9CZD3 Mouse SwissProt: Q5I0G4 Rat Unigene: 404321 Human Unigene: 3338 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
X连锁Charcot-Marie-Tooth神经病变相关蛋白抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 染色质和核信号
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid