神经细胞膜糖蛋白M6a抗体
规格：1mg/1ml
英文名： GPM6A
别名： GPM6A; GPM6A_HUMAN; M6a; M6 a; M6-a; Neuronal membrane glycoprotein M6-a.
分子量： 31kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human GPM6A
交叉反应：Human, Mouse, Rat, Dog, Rabbit,
细胞定位：细胞膜
神经细胞膜糖蛋白M6a抗体产品介绍：Function: Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. GPM6A-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. May be involved in neuronal NGF-dependent Ca(2+) influx. May be involved in regulation of endocytosis and intracellular trafficking of G-protein-coupled receptors 神经细胞膜糖蛋白M6a抗体(GPCRs); enhances internalization and recycling of mu-type opioid receptor. Subunit: Interacts with OPRM1 Subcellular Location: Cell membrane; Multi-pass membrane protein. Cell projection, axon. Cell projection, dendritic spine. Cell projection, filopodium. Note=Localizes to cholesterol-rich lipid rafts of the plasma membrane of hippocampal neurons. Localized to plasma membrane of cell bodies and neurites of hippocampal neurons. Localized in membrane protrusions (filopodia and spines) of primary hippocampal neurons. Localized to the 神经细胞膜糖蛋白M6a抗体growth cone edge membrane of elongating axons. Similarity: Belongs to the myelin proteolipid protein family. Gene ID: 2823 Database links: Entrez Gene: 2823 Human Entrez Gene: 234267 Mouse Omim: 601275 Human SwissProt: P51674 Human SwissProt: P35802 Mouse Unigene: 75819 Human Unigene: 241700 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
神经细胞膜糖蛋白M6a抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:20-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 神经生物学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid