阳离子转运器1抗体
规格：1mg/1ml
英文名： 42644
别名： Organic cation transporter1; NF A1; OCT1; OTF 1; OTF1; PO21; PO2F1; POU domain class 2 transcription factor 1; PO2F1_HUMAN.
分子量： 76kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human OCT1
交叉反应：Human, Mouse, Rat, Pig, Cow, Horse, Rabbit,
细胞定位：
阳离子转运器1抗体产品介绍：background: Oct1 is a transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. It modulates transcription transactivation by NR3C1, AR and PGR and interacts with NR3C1, AR and PGR. Oct1 is Ubiquitous and belongs to the POU transcription factor family class 2 subfamily. Oct1 contains 1 homeobox domain. Function: Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. Modulates transcription transactivation by NR3C1, AR and PGR By similarity. In case of human herpes simplex virus (HSV)阳离子转运器1抗体 infection, POU2F1 forms a multiprotein-DNA complex with the viral transactivator protein VP16 and HCFC1 thereby enabling the transcription of the viral immediate early genes. Subunit: Interacts with NR3C1, AR, PGR and HCFC1. Associates with the herpes simplex virus VP16-induced complex; binding to HCFC1 activates the viral transcriptional activator VP16 for association with POU2F1, to form a multiprotein-DNA complex responsible for activating transcription of the viral immediate early genes. Subcellular Location: Nucleus. Tissue Specificity: Ubiquitous. Isoform 2 is lymphocyte-specific. Post-translational modifications: Phosphorylated by PRKDC. Similarity: Belongs to the POU transcription factor family. 阳离子转运器1抗体Class-2 subfamily. Contains 1 homeobox DNA-binding domain. Contains 1 POU-specific domain. Gene ID: 5451 Database links: Entrez Gene: 5451 Human Entrez Gene: 18986 Mouse Entrez Gene: 171068 Rat Omim: 164175 Human SwissProt: P14859 Human SwissProt: P25425 Mouse SwissProt: P31503 Rat Unigene: 283402 Human Unigene: 245261 Mouse Unigene: 46306 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 同源结构域蛋白（Homeodomain Proteins） OCT-1是OCT转录调节因子家簇中的一员，阳离子转运器-1广泛存在于哺乳动物细胞中。Oct-1是非**细胞中**的八聚体结合因子。
阳离子转运器1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：**学 通道蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid