早期生长应答蛋白1抗体
规格：1mg/1ml
英文名： Egr1
别名： Egr-1; Early growth response 1; Krox-24; Ngf1; Ngfi; NGFI-A; zif-268; Egr1; A530045N19Rik; egr; Egr-1; ETR103; Krox-1; Krox-24; Krox24; NGF1-A; NGFI-A; NGFIA; TIS8; Zenk; Zfp-6; AT 225; AT225; Early g
分子量： 60kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Egr-1 (4
交叉反应：Human, Mouse, Rat,
细胞定位：细胞核
早期生长应答蛋白1抗体产品介绍：background: The protein encoded by this gene belongs to the EGR family of C2H2-type zinc-finger proteins. It is a nuclear protein and functions as a transcriptional regulator. The products of target genes it activates are required for differentitation and mitogenesis. Studies suggest this is a cancer suppresor gene. [provided by RefSeq]. Function: Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'(EGR-site). Activates the transcription of target genes whose products are required 早期生长应答蛋白1抗体for mitogenesis and differentiation. Subcellular Location: Nucleus. Similarity: Belongs to the EGR C2H2-type zinc-finger protein family. Contains 3 C2H2-type zinc fingers. Gene ID: 1958 Database links: Entrez Gene: 1958 Human Entrez Gene: 13653 Mouse Omim: 128990 Human SwissProt: P18146 Human SwissProt: P08046 Mouse Unigene: 326035 Human Unigene: 708393 Human Unigene早期生长应答蛋白1抗体: 181959 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. Egr-1为即刻早期基因家族中的一个成员,是一种含3个锌指结构的转录因子。有研究表明EGR-1在细胞生长分化中发挥重要作用，如在细胞周期G1-S期的转换过程中Egr-1被诱导表达。
早期生长应答蛋白1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 信号转导 生长因子和** 细胞周期蛋白 转录调节因子
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid