阳离子转运蛋白2抗体
规格：1mg/1ml
英文名： 42645
别名： organic cation transporter OCT2; POU domain, class 2, transcription factor 2; Octamer-binding transcription factor 2; Oct-2; OTF-2; Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2; PO
分子量： 51kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from mouse OCT2 (11
交叉反应：Human, Mouse, Rat,
细胞定位：细胞核 细胞浆
阳离子转运蛋白2抗体产品介绍：background: Oct2 is a transcription factor that specifically binds to the octamer motif (5'-ATTTGCAT-3'). Oct2 regulates transcription in a number of tissues in addition to activating immunoglobulin gene expression. It also modulates transcription transactivation by NR3C1, AR and PGR. Oct2 is B cell specific, belongs to the POU transcription factor family class 2 subfamily and contains 1 homeobox domain. Function: Transcription factor that specifically binds to the octamer motif (5'-ATTTGCAT-3'). Regulates transcription in a number of tissues in addition to activating immunoglobulin gene expression. Modulates transcription transactivation by NR3C1, AR and PGR阳离子转运蛋白2抗体. Isoform 5 activates the U2 small nuclear RNA (snRNA) promoter. Subunit: Interacts with NR3C1, AR and PGR. Subcellular Location: Cytoplasm. Nuclear Tissue Specificity: Isoform 3 is B-cell specific. Isoform 5 is expressed in B-cells and the immunoglobulin-expressing T-cell line Molt-4, but not in the T-cell line BW 5147. Similarity: Belongs to the POU transcription factor family. Class-2 subfamily. Contains 1 homeobox DNA-binding domain. Contains 1 POU-specific domain. Gene ID: 18987 Database links: Entrez Gene: 5452 Human Entrez Gene: 18987 Mouse阳离子转运蛋白2抗体 Entrez Gene: 117058 Rat Omim: 164176 Human SwissProt: P09086 Human SwissProt: Q00196 Mouse Unigene: 147381 Human Unigene: 76683 Mouse Unigene: 155998 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 同源结构域蛋白（Homeodomain Proteins） OCT-2是B**细胞转录因子，以**球蛋白启动子为目标，于**中心形成和B细胞分化成浆细胞中起作用。
阳离子转运蛋白2抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid