胸腺素β10抗体
规格：1mg/1ml
英文名： T Beta 10
别名： MIG 12; MIG12; Migration inducing gene 12; Migration inducing protein 12; Ptmb10; TB 10; TB10; Thyb 10; Thyb10; Thymosin beta-10; Thymosin beta 10; TMSB10; TYB10_HUMAN
分子量： 4.9kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human T Beta 1
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse,
细胞定位：细胞浆
胸腺素β10抗体产品介绍：background: The beta thymosins are a family of related peptides, initially isolated from calf thymus but known to be present in a wide variety of mammalian and other vertebrate cells and tissues. Thymosin beta 4 was the first member of the family to be characterized. Although TMSB4 was initially proposed to be a thymic hormone acting at early stages of T cell maturation, the high concentration of the protein and its mRNA in a number of other tissues and cells, as well as the lack of an identifiable secretory signal sequence, 胸腺素β10抗体suggested that it had a general function in many cell types. Thymosin beta 10 is closely related in sequence to TMSB4 and is also an actin sequestering protein. Function: Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Subcellular Location: Cytoplasm, cytoskeleton. Similarity: Belongs to the thymosin beta family. Gene ID: 9168 Database links: Entrez Gene: 9168 Human Entrez Gene: 100364435 Rat Entrez Gene: 50665 Rat Omim: 188399 Human 胸腺素β10抗体SwissProt: P63313 Human SwissProt: Q596K9 Human SwissProt: P63312 Rat Unigene: 446574 Human Unigene: 5983 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 胸腺素β10同其他胸腺素一样也是多肽类**，具有增强细胞**功能和调节**平衡等作用，胸腺素可使由骨髓产生的干细胞转变为T**细胞，因而可增强细胞**功能，对体液**的影响甚微。 近年来研究认为：该蛋白于肿瘤转移有关，胸腺素β10在肿瘤转移潜能的增高伴有肌动蛋白多聚体的丢失和微丝结构的解聚,微丝骨架的这种变化与Tβ10的表达增高具有相关性。
胸腺素β10抗体产品应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 **学 生长因子和**
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid