线粒体脱偶连蛋白1抗体
规格：1mg/1ml
英文名： UCP-1
别名： Uncoupling Protein-1; UCP1; UCP 1; Mitochondrial brown fat uncoupling protein 1; mitochondrial brown fat uncoupling protein; SLC25A7; Thermogenin; UCP 1; UCP; Uncoupling protein 1; UCP1_HUMAN.
分子量： 33kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human UCP-1
交叉反应：Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep,
细胞定位：细胞浆 线粒体
线粒体脱偶连蛋白1抗体产品介绍：background: Mitochondrial uncoupling proteins (UCP) are members of the family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the线粒体脱偶连蛋白1抗体 three homologous protein domains of MACPs. This gene is expressed only in brown adipose tissue, a specialized tissue which functions to produce heat. [provided by RefSeq]. Function: UCP are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation from ATP synthesis. As a result, energy is dissipated in the form of heat.线粒体脱偶连蛋白1抗体 Subunit: Acts as a dimer forming a proton channel. Subcellular Location: Mitochondrion inner membrane; Multi-pass membrane protein. Tissue Specificity: Brown adipose tissue. Similarity: Belongs to the mitochondrial carrier family. Contains 3 Solcar repeats. Gene ID: 7350 Database links: Entrez Gene: 7350 Human Entrez Gene: 22227 Mouse Entrez Gene: 24860 Rat Omim: 113730 Human SwissProt: P25874 Human SwissProt: P12242 Mouse SwissProt: P04633 Rat Unigene: 249211 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
线粒体脱偶连蛋白1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：神经生物学 信号转导 线粒体
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid