乙型肝炎病毒X相关蛋白2抗体
规格：1mg/1ml
英文名： ARA9/XAP2
别名： AH receptor interacting protein; AH receptor-interacting protein; AIP; AIP; AIP_HUMAN; ARA 9; Aryl hydrocarbon receptor interacting protein; Aryl-hydrocarbon receptor-interacting protein; fa03h10; FKB
分子量： 38kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human ARA9
交叉反应：Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep,
细胞定位：细胞浆
乙型肝炎病毒X相关蛋白2抗体产品介绍：background: The protein encoded by this gene is a receptor for aryl hydrocarbons and a ligand-activated transcription factor. The encoded protein is found in the cytoplasm as part of a multiprotein complex, but upon binding of ligand is transported to the nucleus. This protein can regulate the expression of many xenobiotic metabolizing enzymes. Also, the encoded protein can bind specifically to and inhibit the activity of hepatitis B virus. [provided by RefSeq, Sep 2008] Function: signaling, possibly by influencing its receptivity for ligand and/or its nuclear targeting. Cellular negative regulator of the hepatitis B virus (HBV) X protein.May play a positive role in AHR-mediated (aromatic hydrocarbon receptor) Subunit: Interacts with RET in the pituitary gland; this interaction prevents the formation of the AIP-survivin complex. Subcellular Location: Cytoplasm. Tissue Specificity: Widely expressed. Higher levels seen in the heart, placenta and skeletal muscle. 乙型肝炎病毒X相关蛋白2抗体Not expressed in the liver. DISEASE: Defects in AIP are a cause of familial isolated pituitary adenoma (FIPA) [MIM:102200]. Defects in AIP are a cause of growth hormone-secreting pituitary adenoma (GHSPA) [MIM:102200]; also known as familial isolated somatotropinomas (FIS) or isolated familial somatotropinoma (IFS) or familial somatotrophinoma or acromegaly due to pituitary adenoma. Defects in AIP are a cause of ACTH-secreting pituitary adenoma (ASPA) [MIM:219090]; also known as pituitary Cushing disease. A pituary adenoma resulting in excessive production of adrenocorticotropic hormone. This leads to hypersecretion of cortisol by the adrenal glands and ACTH-dependent Cushing syndrome. Clinical manifestations of Cushing syndrome include facial and trunkal obesity, abdominal striae, muscular weakness, osteoporosis, arterial hypertension, diabetes. Defects in AIP are a cause of prolactin-secreting pituitary adenoma (PSPA) [MIM:600634]; also known as prolactinoma. 乙型肝炎病毒X相关蛋白2抗体Prolactin-secreting pituitary adenoma is the most common type of hormonally active pituitary adenoma. Similarity: Contains 1 PPIase FKBP-type domain. Contains 2 TPR repeats. Gene ID: 9049 Database links: Entrez Gene: 9049 Human Entrez Gene: 11632 Mouse Entrez Gene: 282827 Rat Entrez Gene: 360190 Cow Entrez Gene: 610467 Dog Omim: 605555 Human SwissProt: Q7YRC1 Cow SwissProt: O00170 Human SwissProt: O08915 Mouse SwissProt: Q5FWY5 Rat Unigene: 20864 Dog Unigene: 412433 Human Unigene: 10433 Mouse Unigene: 95160 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
乙型肝炎病毒X相关蛋白2抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 神经生物学 **及病毒
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid