回肠脂肪酸结合蛋白抗体
规格:1mg/1ml
英文名: FABP6
别名: Fatty acid binding protein 6, ileal (gastrotropin); Gastrotropin; GT antibody I 15P; I BABP; I BALB; I BAP; I15P; IBABP; IBALB; IBAPv ILBP; ILBP3; Ileal lipid binding protein; ILLBP; Intestinal 15 kDa
分子量: 14kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human FABP6
交叉反应:Human, Mouse, Rat, Horse, Rabbit,
细胞定位:细胞浆
回肠脂肪酸结合蛋白抗体产品介绍:background: This gene encodes the ileal fatty acid binding protein. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABP6 and FABP1 (the liver fatty acid binding protein) are also able to bind bile acids. It is thought that FABPs roles include fatty acid uptake, transport, and metabolism. Transcript variants generated by alternate transcription promoters and/or alternate splicing have been found for this gene. [provided by RefSeq, Jul 2008] Function: Ileal protein which stimulates gastric acid and pepsinogen secretion. Seems to be able to bind to bile salts and bilirubins. 回肠脂肪酸结合蛋白抗体Isoform 2 is essential for the survival of colon cancer cells to bile acid-induced apoptosis. Subcellular Location: Cytoplasm and Cytoplasm. Localized close to nucleus on the apical side of both normal and neoplastic cells Tissue Specificity: Isoform 2 is expressed in colorectal adenocarcinomas and their adjacent normal mucosa (at protein level). Isoform 1 is expressed in the jejunum, ileum, cecum and 回肠脂肪酸结合蛋白抗体ascending colon intestine. Isoform 2 is expressed in the gallbladder, duodenum, jejunum, ileum, cecum, ascending, transverse and descending colon, sigmoid colon and rectum. Similarity: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. Gene ID: 2172 Database links: Entrez Gene: 2172?/span>Human Omim: 600422?/span>Human SwissProt: P51161?/span>Human SwissProt: P50119?/span>Rabbit Unigene: 519719?/span>Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
回肠脂肪酸结合蛋白抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 **学
储存条件: Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid