谷氨酰胺转胺酶K抗体
规格:1mg/1ml
英文名: CCBL1
别名: Beta lyase; Beta lysase, kidney; CCBL 1; Cysteine conjugate beta lyase; Cysteine conjugate beta lyase, cytoplasmic; Cysteine conjugate beta lyase; cytoplasmic (glutamine transaminase K, kyneurenine am
分子量: 48kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human CCBL1
交叉反应:Human, Horse, Rabbit,
细胞定位:细胞浆
谷氨酰胺转胺酶K抗体产品介绍:background: This gene encodes a cytosolic enzyme that is responsible for the metabolism of cysteine conjugates of certain halogenated alkenes and alkanes. This metabolism can form reactive metabolites leading to nephrotoxicity and neurotoxicity. Increased levels of this enzyme have been linked to schizophrenia. Multiple transcript variants that encode 谷氨酰胺转胺酶K抗体different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008] Function: Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA). Metabolizes the cysteine conjugates of certain halogenated alkenes and alkanes to form reactive metabolites. Catalyzes the beta-elimination of S-conjugates and Se-conjugates of L-(seleno)cysteine, 谷氨酰胺转胺酶K抗体resulting in the cleavage of the C-S or C-Se bond. Subunit: Homodimer. Subcellular Location: Cytoplasm. Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Gene ID: 883 Database links: Entrez Gene: 883 Human Omim: 600547 Human SwissProt: Q16773 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
谷氨酰胺转胺酶K抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 信号转导 新陈代谢
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid