微管卷曲蛋白SYNC抗体
规格:1mg/1ml
英文名: SYNC
别名: Intermediate filament protein syncoilin; SYNC; SYNC1; SYNCI_HUMAN; Syncoilin; Syncoilin intermediate filament 1; Syncoilin-1.
分子量: 55kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human SYNC/Syn
交叉反应:Human, Mouse, Rat, Chicken, Dog, Pig, Cow,
细胞定位:细胞浆
微管卷曲蛋白SYNC抗体产品介绍:background: Syncoilin (SYNC) is a 483 amino acid member of the intermediate filament family. Localized to the perinuclear region of cytoplasm, Syncoilin interacts with Alpha-Dystrobrevin and Desmin. Syncoilin links the dystrophin associated protein complex (DAPC) to desmin filaments in muscle, and is therefore found at high levels in cardiac and skeletal muscle. Syncoilin is upregulated at the sarcolemma in individuals with various forms of neuromuscular disease. The gene that encodes Syncoilin maps to human 微管卷曲蛋白SYNC抗体chromosome 1, which is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Subunit: Interacts with DES and DTNA. Subcellular Location: Cytoplasm, perinuclear region. 微管卷曲蛋白SYNC抗体Similarity: Belongs to the intermediate filament family. Database links: UniProtKB/Swiss-Prot: Q9H7C4.3 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
微管卷曲蛋白SYNC抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:50-200 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:神经生物学 信号转导 细胞外基质
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid