肿瘤/睾丸抗原135抗体
规格:1mg/1ml
英文名: CT135/ODF3
别名: Cancer/testis antigen 135; CT135; hSHIPPO; odf3; ODF3A_HUMAN; Outer dense fiber of sperm tails 3; Outer dense fiber of sperm tails protein 3; Outer dense fiber protein 3; SHIPPO1; Sperm tail protein S
分子量: 28kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human ODF3/CT1
交叉反应:Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep,
细胞定位:细胞浆
肿瘤/睾丸抗原135抗体产品介绍:background: Outer dense fibers are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail. May help to maintain the passive elastic structures and elastic recoil of the sperm tail. Constituting the main cytoskeletal structure of spermatid flagella, outer dense fibers (ODFs) add elastic recoil, stiffness and protection against shear forces during sperm movement. Human ODFs consist of approximately 10 major and at least 15 minor proteins. The major proteins of the ODF include Odf1, Odf2, and Odf3, which compose a family of proteins that are preferentially expressed during mammalian spermiogenesis. Odf3 (outer dense fiber protein 3), also known as sperm tail protein SHIPPO 1 and TISP50 (transcript induced in spermiogenesis protein 50), is a 254 amino acid protein that is expressed during the latter part of spermatogenesis in flagella of elongated spermatids and mature sperm肿瘤/睾丸抗原135抗体. Odf proteins are directed to their exact subcellular location by Spags, which are characterized as chaperone-like Odf-binding molecules. There are two isoforms of Odf3 that are produced as a result of alternative splicing events. Function: Outer dense fibers are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail. May help to maintain the passive elastic structures and elastic recoil of the sperm tail. Subcellular Location: Cytoplasm. Expressed in the cytoplasmic lobe of spermatids. Tissue Specificity: 肿瘤/睾丸抗原135抗体Testis-specific. Similarity: Belongs to the ODF3 family. Contains 2 STPGR (Sperm-tail PG-rich) repeats. Gene ID: 113746 Database links: Entrez Gene: 113746 Human Entrez Gene: 69287 Mouse Omim: 608356 Human SwissProt: Q96PU9 Human SwissProt: Q920N1 Mouse Unigene: 350949 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产肿瘤/睾丸抗原135抗体品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 发育生物学 细胞周期蛋白 细胞分化
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid