T细胞急性**母细胞白血病相关抗原1抗体
规格：1mg/1ml
英文名： TALLA-1
别名： CD231 antigen; Cell surface glycoprotein A15; Membrane component X chromosome surface marker 1; T cell acute lymphoblastic leukemia associated antigen 1; TALLA 1; TALLA1; Tetraspanin 7; Tetraspanin-7;
分子量： 28kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Tetraspa
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位：细胞膜
T细胞急性**母细胞白血病相关抗原1抗体产品介绍：background: Tetraspanins are a group of hydrophobic membrane proteins that interact with a wide variety of proteins including intracellular signaling molecules, integrins and membrane receptors. TSPAN7 (tetraspanin 7), also known as MXS1 (membrane component chromosome X surface marker 1) or TM4SF2 (transmembrane 4 superfamily member 2), is a 249 amino acid multi-pass membrane protein belonging to the tetraspanin (TM4SF) family of transmembrane proteins. TSPAN7 is believed to play a role in cell motility and cell proliferation. The gene that encodes TSPAN7 maps to human chromosome X and defects in this gene are a cause of mental retardation X-linked type 58 (MRX58), which is characterized by dramatically below average general intellectual functioning. T细胞急性**母细胞白血病相关抗原1抗体Function: May be involved in cell proliferation and cell motility. Subunit: Interacts with herpes simplex virus 1 (HHV-1) UL35. Subcellular Location: Membrane; Multi-pass membrane protein. Tissue Specificity: Not solely expressed in T-cells. Expressed in acute myelocytic leukemia cells of some patients. DISEASE: Defects in TSPAN7 are the cause of mental retardation X-linked type 58 (MRX58) [MIM:300210]. Mental retardation is characterized by significantly sub-average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. Non-syndromic mental retardation patients do not manifest other clinical signs. T细胞急性**母细胞白血病相关抗原1抗体Similarity: Belongs to the tetraspanin (TM4SF) family. Database links: UniProtKB/Swiss-Prot: P41732.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
T细胞急性**母细胞白血病相关抗原1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 信号转导 细胞表面分子
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid