四分子交联体10抗体
规格：1mg/1ml
英文名： TSPAN10
别名： OCSP; oculospanin; tetraspanin 10; Tspan 10; TSN10_HUMAN.
分子量： 36kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human TSPAN10/
交叉反应：Human, Mouse, Rat,
细胞定位：细胞膜
四分子交联体10抗体产品介绍：background: The tetraspanins are integral membrane proteins expressed on cell surface and granular membranes of hematopoietic cells and are components of multi-molecular complexes with specific integrins. Oculospanin, also known as tetraspanin 10 (TSPAN10) or OCSP, is a 355 amino acid multi-pass membrane protein belonging to the tetraspanin (TM4SF) family. Oculospanin is expressed in certain regions of the eye such as retinal pigment epithelium, ciliary body and iris, but is not found in the lens. The gene encoding Oculospanin maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Malfunction or loss of p53 expression is associated with malignant 四分子交联体10抗体cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, and is liked to predisposition of cancers of the ovary, colon, prostate gland and fallopian tubes. Subcellular Location: Membrane; Multi-pass membrane protein四分子交联体10抗体 (Potential). Tissue Specificity: Expressed in the eye, including iris, ciliary body, retinal pigment epithelium, but not lens (protein level). Similarity: Belongs to the tetraspanin (TM4SF) family. Gene ID: 83882 Database links: Entrez Gene: 83882 Human SwissProt: Q9H1Z9 Human Unigene: 208219 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
四分子交联体10抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 神经生物学 细胞分化
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid