DCAF13蛋白抗体
规格：1mg/1ml
英文名： DCAF13
别名： DCA13_HUMAN; DCAF13; DDB1 and CUL4 associated factor 13; DDB1- and CUL4-associated factor 13; DKFZP564O0463; GM83; HSPC064; WD repeat and SOF domain-containing protein 1; WD repeats and SOF1 domain co
分子量： 51kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human DCAF13
交叉反应：Human, Mouse, Rat, Dog, Horse,
细胞定位：细胞核
DCAF13蛋白抗体产品介绍：background: Made up of nearly 146 million bases, chromosome 8 encodes about 800 genes. Translocation of portions of chromosome 8 with amplifications of the c-Myc gene are found in some leukemias and lymphomas, and typically associated with a poor prognosis. Portions of chromosome 8 have been linked to schizophrenia and bipolar disorder. Trisomy 8, also known as Warkany syndrome 2, most often results in early miscarriage but is occasionally seen in a mosaic form in surviving patients who suffer to a varying degree from a number of symptoms including retarded mental and motor development, and certain facial and developmental defects. DCAF13蛋白抗体WRN is a DNA helicase encoded by chromosome 8 and shown defective in those with the early aging disorder Werner syndrome. Chromosome 8 is also associated with Pfeiffer syndrome, congenital hypothyroidism and Waardenburg syndrome. Function: Possible role in ribosomal RNA processing (By similarity). May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex. Subunit: Interacts with DDB1. Subcellular Location: Nucleus, nucleolus (By similarity). Similarity: Contains 7 WD repeats. Gene ID: 25879 Database links: Entrez Gene: DCAF13蛋白抗体25879 Human Entrez Gene: 223499 Mouse Entrez Gene: 100173913 Orangutan SwissProt: Q5ZLK1 Chicken SwissProt: Q9NV06 Human SwissProt: Q6PAC3 Mouse SwissProt: Q5R4T8 Orangutan Unigene: 532265 Human Unigene: 321937 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
DCAF13蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid