碳水化合物激酶结构域蛋白质抗体
规格：1mg/1ml
英文名： CARKD
别名： Carbohydrate kinase domain containing; carbohydrate kinase domain-containing protein; FLJ10769; LP3298; NNRD_HUMAN.
分子量： 37kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human CARKD
交叉反应：Human, Mouse, Rat,
细胞定位：细胞浆
碳水化合物激酶结构域蛋白质抗体产品介绍：background: CARKD is a 347 amino acid protein that belongs to the YjeF family and exists as three alternatively spliced isoforms. Containing one YjeF C-terminal domain, CARKD is encoded by a gene that maps to human chromosome 13q34. Chromosome 13 contains around 114 million base pairs and 400 genes. Key tumor suppressor genes on chromosome 13 include the breast cancer susceptibility gene, BRCA2, and the RB1 (retinoblastoma) gene. RB1 encodes a crucial tumor suppressor protein which, when defective, leads to malignant growth in the retina and has been implicated in a variety of other cancers. The gene SLITRK1, which is associated with Tourette syndrome, is on chromosome 13. As with most chromosomes, polysomy of part or all of chromosome 13 is deleterious to development and decreases the odds of survival. Trisomy 13, also known as Patau syndrome, is quite deadly and the few who 碳水化合物激酶结构域蛋白质抗体survive past one year suffer from permanent neurologic defects, difficulty eating and vulnerability to serious respiratory infections. Function: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity). Subcellular Location: Mitochondrion (By similarity). 碳水化合物激酶结构域蛋白质抗体Similarity: Belongs to the nnrD/CARKD family. Contains 1 YjeF C-terminal domain. Gene ID: 64921 Database links: Entrez Gene: 64921 Human Entrez Gene: 213819 Mouse Omim: 611686 Human SwissProt: Q96PB1 Human SwissProt: Q7TN73 Mouse Unigene: 260041 Human Unigene: 270703 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
碳水化合物激酶结构域蛋白质抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid