香叶烯基转移酶1β抗体
规格：1mg/1ml
英文名： PGGT1B
别名： PGGT1B; GGTase-I beta; GGTase-1 beta; BGGI; Geranylgeranyl transferase type I subunit beta; Geranylgeranyl transferase type-1 subunit beta; GGTase-I-beta; GGTI; PGGT1B; PGTB1_HUMAN; Type I protein ger
分子量： 42kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human PGGT1 be
交叉反应：Human, Mouse, Rat, Horse,
细胞定位：
香叶烯基转移酶1β抗体产品介绍：background: Protein geranylgeranyltransferase type I (GGTase-I) transfers a geranylgeranyl group to the cysteine residue of candidate proteins containing a C-terminal CAAX motif in which 'A' is an aliphatic amino acid and 'X' is leucine (summarized by Zhang et al., 1994 [PubMed 8106351]). The enzyme is composed of a 48-kD alpha subunit (FNTA; MIM 134635) and a 43-kD beta subunit, encoded by the PGGT1B gene. The FNTA gene encodes the alpha subunit for both GGTase-I and the related enzyme farnesyltransferase.[supplied by OMIM, Mar 2010] Function: Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to a 香叶烯基转移酶1β抗体cysteine at the fourth position from the C-terminus of proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. Acts on the Rac1, Rac2, Rap1A and Rap1B proteins. The beta subunit is responsible for peptide-binding. Subunit: Heterodimer of an alpha and a beta subunit. Similarity: Belongs to the protein prenyltransferase subunit beta family. Contains 4 PFTB repeats. Gene ID: 5229 Database links: Entrez 香叶烯基转移酶1β抗体Gene: 5229 Human Entrez Gene: 225467 Mouse Entrez Gene: 81746 Rat Omim: 602031 Human SwissProt: P53609 Human SwissProt: Q8BUY9 Mouse SwissProt: P53610 Rat Unigene: 254006 Human Unigene: 262096 Mouse Unigene: 393044 Mouse Unigene: 10031 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
香叶烯基转移酶1β抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid