MYC结合蛋白2抗体
规格：1mg/1ml
英文名： MYCBP2
别名： Pam/highwire/rpm-1 protein; Phr1; MYC binding protein 2; PAM; Pam, highwire, rpm 1; Protein associated with Myc; Probable E3 ubiquitin-protein ligase MYCBP2; Myc-binding protein 2; Pam/highwire/rpm-1
分子量： 510kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human MYCBP2
交叉反应：Human, Mouse, Rat, Dog, Horse, Sheep,
细胞定位：细胞核
MYC结合蛋白2抗体产品介绍：background: MYCBP2 belongs to the highwire family. It is a probable E3 ubiquitin-protein ligase which mediates ubiquitination and subsequent proteasomal degradation of target proteins. MYCBP2 may function as a facilitator or regulator of transcriptional activation by MYC and have a role during synaptogenesis. There are two different isoforms. Function: Probable E3 ubiquitin-protein ligase which mediates ubiquitination and subsequent proteasomal degradation of target proteins. May function as a facilitator or regulator of transcriptional activation by MYC. May have a role during synaptogenesis. Subunit: Interacts with MYC. Interacts with TSC2 (tuberin) when TSC2 is in complex with TSC1 (hamartin). Interacts with FBXO45. Subcellular Location: Nuclear Tissue Specificity: Expressed in all tissues examined, MYC结合蛋白2抗体expression is exceptionally abundant in brain and thymus. Colocalizes with TSC1 and TSC2 along the neurites and in the growth cones. Colocalized with TSC1 in one of the filopodial extensions at the tip of a growth cone. Similarity: Belongs to the highwire family. Contains 1 B box-type zinc finger. Contains 1 DOC domain. Contains 1 filamin repeat. Contains 5 RCC1 repeats. Contains 1 RING-type zinc finger. Gene ID: MYC结合蛋白2抗体23077 Database links: Entrez Gene: 23077 Human Entrez Gene: 105689 Mouse Entrez Gene: 290447 Rat Omim: 610392 Human SwissProt: O75592 Human SwissProt: Q7TPH6 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
MYC结合蛋白2抗体产品应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 细胞周期蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid