肌肉特定环指蛋白3抗体
规格：1mg/1ml
英文名： MURF3
别名： MURF 3; MURF; MURF-3; MuRF3; Muscle specific RING finger protein 3; Muscle specific RING finger protein; Muscle specific RING finger protein homolog; Muscle-specific RING finger protein 3; Muscle-spec
分子量： 40kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human MURF3
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Rabbit,
细胞定位：细胞浆
肌肉特定环指蛋白3抗体产品介绍：background: MuRF1, is a nuclear protein that interacts with SMT3b and the large myofibrillar protein Titin. In muscle cells, MuRF2 (RFN29) regulates gene expression and protein turnover. It localizes to the cytoplasm, but under atrophic conditions it is detected in the nucleus. MuRF2 can form oligomers with various other proteins, including Titin and Myosin. MuRF3, also designated tripartite motif-containing 54 (TRIM54) or ring finger protein 30 (RNF30), interacts with tubulin and stabilizes microtubules duing myotube formation. It is a cytoplasmic protein the localizes to the Z-lines in skeletal muscles, while MuRF2 localizes to the sarcomeric M-band in cardiomyocytes. 肌肉特定环指蛋白3抗体MuRF3 shares 77% and 65% sequence identity with MuRF1 and MuRF2, respectively. MuRF1-3 share a conserved N-terminal RING domain and zinc-binding B-box motif, and two coiled-coil dimerization motif boxes, in their central regions. Function: May bind and stabilize microtubules during myotubes formation (By similarity). Subunit: Homooligomer and heterooligomer. Interacts with tubulin. Interacts with TRIM63 and probably with TRIM55. Subcellular Location: Cytoplasm Tissue Specificity: Specifically expressed in heart and skeletal muscle. Similarity肌肉特定环指蛋白3抗体: Contains 1 B box-type zinc finger. Contains 1 COS domain. Contains 1 RING-type zinc finger. Gene ID: 57159 Database links: Entrez Gene: 57159 Human Omim: 606474 Human SwissProt: Q9BYV2 Human Unigene: 516036 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
肌肉特定环指蛋白3抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid