蛋白酶体PSMα2抗体
规格：1mg/1ml
英文名： Proteasome 20S alpha 2
别名： 20S Proteasome α2; HC3; Macropain subunit C3; MU antibody Multicatalytic endopeptidase complex subunit C3; PMSA2; Proteasome (prosome macropain) subunit alpha type 2; Proteasome alpha 2 subunit; Prote
分子量： 26kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Proteaso
交叉反应：Human, Mouse, Rat, Chicken, Cow, Rabbit, Sheep,
细胞定位：细胞核 细胞浆
蛋白酶体PSMα2抗体产品介绍：background: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. PSMA2 may have a potential regulatory effect on another component(s) of the proteasome complex through tyrosine phosphorylation. Function: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. PSMA2 may have a potential regulatory effect on another component(s) of the proteasome complex through tyrosine phosphorylation. Subunit: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed蛋白酶体PSMα2抗体 of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel. Subcellular Location: Cytoplasm. Nucleus. Cytoplasm, P-body (By similarity). Note=Co-localizes with TRIM5 in the cytoplasmic bodies (By similarity). Post-translational modifications: Phosphorylated on tyrosine residues; which may be important for nuclear import (By similarity).蛋白酶体PSMα2抗体 Similarity: Belongs to the peptidase T1A family. Gene ID: 5683 Database links: Entrez Gene: 5683 Human Entrez Gene: 19166 Mouse Entrez Gene: 29669 Rat Omim: 176842 Human SwissProt: P25787 Human SwissProt: P49722 Mouse SwissProt: P17220 Rat Unigene: 333786 Human Unigene: 252255 Mouse Unigene: 1617 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
蛋白酶体PSMα2抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid