蛋白酶体PSMα6抗体
规格：1mg/1ml
英文名： Proteasome 20S alpha 6
别名： 27 kDa prosomal protein; HC2; IOTA; Macropain iota chain; Macropain subunit iota; Multicatalytic endopeptidase complex iota chain; p27K; PROS 27; PROS27; Prosomal P27K protein; Proteasome (prosome mac
分子量： 27kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Proteaso
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Horse, Sheep,
细胞定位：细胞核 细胞浆
蛋白酶体PSMα6抗体产品介绍：background: The gene encodes a 246-amino acid polypeptide containing an RNA binding motif, a putative nuclear localization signal, and phosphorylation sites. The alpha subunits comprises the outer rings of the proteasome. Some alpha subunits contain a functional nuclear localization signal; proteasomes are found in both the nuclear and cytoplasmic compartments of the cell. Alpha subunits may constitute a physical barrier that limits access of cytosolic proteins into the inner proteolytic chamber. Function: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. Subunit: The 26S proteasome consists 蛋白酶体PSMα6抗体of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel. Subcellular Location:蛋白酶体PSMα6抗体 Cytoplasm. Nucleus. Cytoplasm, P-body (By similarity). Note=Co-localizes with TRIM5 in the cytoplasmic bodies (By similarity). Similarity: Belongs to the peptidase T1A family. Gene ID: 5687 Database links: Entrez Gene: 5687 Human Entrez Gene: 26443 Mouse Entrez Gene: 29673 Rat Omim: 602855 Human SwissProt: P60900 Human SwissProt: Q9QUM9 Mouse SwissProt: P60901 Rat Unigene: 446260 Human Unigene: 30210 Mouse Unigene: 107278 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复） not yet tested in other 蛋白酶体PSMα6抗体applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 细胞周期蛋白 细胞分化
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid