膜相关环指蛋白6抗体
规格：1mg/1ml
英文名： 42435
别名： Doa10 homolog; E3 ubiquitin protein ligase MARCH6; MARCH 6; MARCH VI; MARCHVI; Membrane associated RING CH protein VI; Membrane associated ring finger (C3HC4) 6; Membrane associated RING finger protei
分子量： 103kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human MARCH6
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Zebrafish, Sheep,
细胞定位：细胞浆 细胞膜
膜相关环指蛋白6抗体产品介绍：background: MARCH6 (Membrane associated RING finger protein 6) belongs to the MARCH family, which contains at least seven membrane associated RING-CH (MARCH)proteins. MARCH proteins are E3 ubiquitin ligases and are located to subcellular membranes. Function: E3 ubiquitin-protein ligase that promotes ubiquitination of DIO2, leading to its degradation.膜相关环指蛋白6抗体 E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. May cooperate with UBE2G1. Subunit: Interacts with DIO2. Subcellular Location: Endoplasmic reticulum membrane; Multi pass membrane protein. Tissue Specificity: Present in brain (at protein level). Post-translational modifications: Auto-ubiquitinated膜相关环指蛋白6抗体, which results in proteasomal degradation. Similarity: Contains 1 RING-CH-type zinc finger. Gene ID: 10299 Database links: Entrez Gene: 10299 Human Entrez Gene: 223455 Mouse Entrez Gene: 294862 Rat Omim: 613297 Human SwissProt: O60337 Human SwissProt: Q6ZQ89 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
膜相关环指蛋白6抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 细胞周期蛋白 通道蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid