着丝粒蛋白O抗体
规格：1mg/1ml
英文名： CENPO
别名： CENPO binds to the kinetochore. Its depletion from cells interferes with spindle assembly. It is necessary for correct binding of spindle checkpoint proteins to kinetochores. It is required for checkp
分子量： 34kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human CENPO
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep,
细胞定位：细胞核
着丝粒蛋白O抗体产品介绍：background: CENPO binds to the kinetochore. Its depletion from cells interferes with spindle assembly. It is necessary for correct binding of spindle checkpoint proteins to kinetochores. It is required for checkpoint signaling. Function: Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex. Modulates the kinetochore-bound levels of NDC80 complex. Subunit: Component of the CENPA-CAD着丝粒蛋白O抗体 complex, composed of CENPI, CENPK, CENPL, CENPO, CENPP, CENPQ, CENPR and CENPS. The CENPA-CAD complex interacts with the CENPA-NAC complex, at least composed of CENPA, CENPC, CENPH, CENPM, CENPN, CENPT and MLF1IP/CENPU. Subcellular Location: Nucleus. Chromosome, centromere. Chromosome, centromere, kinetochore. Note=The CENPA-CAD complex is probably recruited on centromeres by the CENPA-NAC complex. Gene ID: 79172 Database links: Entrez Gene: 79172 Human Entrez Gene: 52504 Mouse Omim: 611504 Human SwissProt:着丝粒蛋白O抗体 Q9BU64 Human SwissProt: Q8K015 Mouse Unigene: 731569 Human Unigene: 70546 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
着丝粒蛋白O抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 细胞周期蛋白 细胞分化 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid
- 温馨提示：为规避购买风险，建议您在购买前务必确认供应商资质与产品质量。
- 免责申明：以上内容为注册会员自行发布，若信息的真实性、合法性存在争议，平台将会监督协助处理，欢迎举报