G蛋白信号调节蛋白2抗体
规格：1mg/1ml
英文名： GPSM2
别名： vDFNB82; G protein signalling modulator 2 (AGS3 like C. elegans); G protein signalling modulator 2; G-protein-signaling modulator 2; Gpsm2; GPSM2_HUMAN; HGNC:29501; LGN; LGN protein; Mosaic protein LG
分子量： 77kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human GPSM2
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Zebrafish, Sheep,
细胞定位：细胞浆
G蛋白信号调节蛋白2抗体产品介绍：background: Plays an important role in spindle pole orientation. Interacts and contributes to the functional activity of G(i) alpha proteins. Acts to stabilize the apical complex during neuroblast divisions. Function: lays an important role in spindle pole orientation. Interacts and contributes to the functional activity of G(i) alpha proteins. Acts to stabilize the apical complex during neuroblast divisions. Subunit: Interacts with LLGL2. Interacts with INSC/inscuteable and probably with F2RL2. Subcellular Location: Cytoplasm. Cytoplasm, cell cortex. Note=Localizes in the cytoplasm in the interphase and at cell periphery in the metaphase. Tissue Specificity: Ubiquitously expressed. Post-translational modifications: Defects in GPSM2 are the cause of Chudley-McCullough syndrome (CMCS) [MIM:604213]. An autosomal recessive G蛋白信号调节蛋白2抗体neurologic disorder characterized by early-onset sensorineural deafness and specific brain anomalies on MRI, including hypoplasia of the corpus callosum, enlarged cysterna magna with mild focal cerebellar dysplasia, and nodular heterotopia. Some patients have hydrocephalus. Psychomotor development is normal. Similarity: Belongs to the GPSM family. Contains 4 GoLoco domains. Contains 8 TPR repeats. Gene ID: G蛋白信号调节蛋白2抗体29899 Database links: Entrez Gene: 29899 Human Entrez Gene: 76123 Mouse Entrez Gene: 362021 Rat Omim: 609245 Human SwissProt: P81274 Human SwissProt: Q8VDU0 Mouse Unigene: 584901 Human Unigene: 658489 Human Unigene: 226941 Mouse Unigene: 144235 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
G蛋白信号调节蛋白2抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 神经生物学 信号转导 细胞周期蛋白 细胞分化 G蛋白信号
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid