21号染色体开放阅读框106抗体
规格：1mg/1ml
英文名： C21orf106/DIP2A
别名： C21orf106; DIP 2A; DIP2; DIP2 disco interacting protein 2 homolog A; DIP2 homolog A; DIP2A; DIP2 like protein; Disco interacting protein 2 homolog; KIAA0184; DIP2A_HUMAN.
分子量： 170kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human DIP2A/C2
交叉反应：Human, Mouse, Rat, Chicken, Cow, Sheep,
细胞定位：细胞核
21号染色体开放阅读框106抗体产品介绍：background: DIP2A, also known as DIP2, is a 1571 amino acid nuclear protein. It is one of three human homologs (DIP2A, DIP2B and DIP2C) of the Drosophila dip2 (disconnected-interacting protein 2) protein. In Drosophila, dip2 interacts with disco, a protein required for neuronal connections in the visual systems of larvae and *****s. The closest vertebrate homologs to disco are the basonuclin genes. In mice, DIP2 homologs show restricted expression to the brain. This suggests that, similar to the 21号染色体开放阅读框106抗体function of Drosophila dip2, vertebrate DIP2 homologs may play a role in the development of the nervous system. Expressed ubiquitously with highest expression in the brain, DIP2A is thought to function in signaling throughout the central nervous system by providing positional clues for axon patterning and pathfinding. Four isoforms of DIP2A exist due to alternative splicing events. Function: May provide positional cues for axon pathfinding and patterning in the central nervous system. Subcellular Location: Nuclear Tissue Specificity: Low expression in all tissues tested.21号染色体开放阅读框106抗体 Similarity: Belongs to the DIP2 family. Gene ID: 23181 Database links: Entrez Gene: 23181 Human Entrez Gene: 64451 Mouse Omim: 607711 Human SwissProt: Q14689 Human SwissProt: Q8BWT5 Mouse Unigene: 189585 Human Unigene: 33183 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
21号染色体开放阅读框106抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 细胞周期蛋白 转录调节因子 细胞分化 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid